Question 1

Why have I been prescribed Letoval Tablet?

Accepted Answer

Letoval Tablet is an aromatase inhibitor. It is generally prescribed to treat breast cancer in women who no longer have periods, either due to menopause or after surgery or chemotherapy.

Question 2

How does Letoval Tablet work?

Accepted Answer

Letoval Tablet is also known as an anti-estrogen drug. It is called so because it acts by reducing the production of estrogen in your body by blocking the enzyme aromatase, which is responsible for the production of estrogen. Estrogen stimulates the production of certain types of breast cancer in your body. These cancers are called "estrogen-dependent cancers". Reducing the production of estrogen may prevent cancer from growing.

Question 3

For how long should I take Letoval Tablet?

Accepted Answer

If the breast tumor is in the advanced stage or has spread to other parts of the body, it is recommended that you continue taking Letoval Tablet till the tumor shows progression. In cases where Letoval Tablet is given after tamoxifen (another anti-estrogen used for breast cancer) or surgery, it should be given for 5 years or until the tumor comes back, whichever is first. It can also be given as a sequential treatment; 2 years of Letoval Tablet followed by 3 years of tamoxifen.

Question 4

If I am taking irbesartan to control my blood pressure, can I take Letoval Tablet?

Accepted Answer

Yes, you can take irbesartan and Letoval Tablet together. However, be careful and keep a regular check on your blood pressure since Letoval Tablet may increase your blood pressure. Consult your doctor in case you have problems controlling your blood pressure.

Question 5

Does Letoval Tablet affect vision?

Accepted Answer

Although it is very uncommon, Letoval Tablet may cause a cataract. So, if you experience blurred vision or eye irritation, consult your doctor immediately.

Question 6

My friend who is taking Letoval Tablet often sweats a lot. Is it because of Letoval Tablet?

Accepted Answer

This could be a sign of hot flushes which is a very common side effect of Letoval Tablet. It happens due to decreased estrogen levels. The frequency of hot flushes reduces once your body adjusts to Letoval Tablet. However, in some people, the flushes and sweats may continue during the treatment and stop a few months after the treatment finishes. You can consult your doctor who will provide you a remedy if it is very bothersome.

Question 7

What are the serious side effects of Letoval Tablet?

Accepted Answer

The serious side effects do not occur in everyone and very few people experience them. The serious side effects of Letoval Tablet include stroke, angina, heart attack, blood clotting, cataract, osteoporosis, and severe skin reactions.

Question 8

Does Letoval Tablet cause bone loss?

Accepted Answer

Letoval Tablet may cause thinning or wasting of your bones (osteoporosis), which is due to the decrease in estrogen levels in your body. Your doctor may decide to measure your bone density (a way of monitoring for osteoporosis) before, during and after treatment.

Question 9

Can I take Letoval Tablet for induction of ovulation in anovulatory infertility?

Accepted Answer

As per the Ministry of Health and Family Welfare, Letoval Tablet is restricted for use in induction of ovulation in anovulatory infertility.

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