Question 1

What are the serious side effects of Canmab 440mg Injection?

Accepted Answer

There are various side effects related to Canmab 440mg Injection such as sore throat, fever, chills, excessive tiredness, pale skin, nosebleeds, and other unusual bruising or bleeding. One can also  experience stomach pain, seizures, hallucinations, muscle cramps, and spasms. Along with that, nausea or vomiting, loss of appetite, fatigue, rapid heart beat, discoloration of urine; decreased amount of urine, difficulty in  urinating, pain when urinating, and other signs of infection can also be observed with the use of Canmab 440mg Injection. You should call your doctor immediately if you notice any such symptoms.

Question 2

How long after Canmab 440mg Injection therapy can I get pregnant?

Accepted Answer

Women of child-bearing age should use effective contraception during Canmab 440mg Injection therapy and for 7 months after completing the treatment. You can plan your pregnancy after 7 months of treatment with Canmab 440mg Injection.

Question 3

How long should Canmab 440mg Injection be taken?

Accepted Answer

Patients with early breast cancer should take Canmab 440mg Injection for 1 year or until disease recurs, whichever occurs first. It is not advised to extend the treatment beyond 1 year in patients of early breast cancer.

Question 4

Is fasting required before administering Canmab 440mg Injection?

Accepted Answer

No, fasting is not required before administering Canmab 440mg Injection. It should be given under the guidance of a doctor who is experienced in giving cancer chemotherapy and should be given only by a healthcare professional.

Question 5

How is Canmab 440mg Injection given, intravenously or intramuscularly?

Accepted Answer

There are 2 different formulations available for administration of Canmab 440mg Injection, one is given as an infusion into a vein (intravenous infusion) and the other is given as an injection under the skin (subcutaneous injection). It is important to check the product labels to ensure that the correct formulation is being given as prescribed. Canmab 440mg Injection intravenous formulation is not for subcutaneous use and should be given as an intravenous infusion only. Your doctor may consider switching your Canmab 440mg Injection intravenous treatment to Canmab 440mg Injection subcutaneous treatment (and vice versa) if considered appropriate for you.

Question 6

Can Canmab 440mg Injection be given to HER2 negative cancer patients?

Accepted Answer

No, Canmab 440mg Injection cannot be given in patients with HER2 negative cancer cells. Canmab 440mg Injection belongs to class of monoclonal antibody. It binds selectively to a protein called human epidermal growth factor receptor 2 (HER2). HER2 is found, in large amounts, on the surface of some cancer cells. When Canmab 440mg Injection binds to HER2, it stops the growth and spread of the cancer cells. Therefore, it is only effective in HER2 positive patients (in which HER2 is present) and will not be beneficial for HER2 negative patients (in which HER2 is not present).

Question 7

Why has my doctor advised for investigations of heart?

Accepted Answer

Canmab 440mg Injection when used with anthracycline class of anti-cancer medicines (eg doxorubicin) may adversely affect your heart. Hence, your doctor needs to check the health of your heart initially before starting treatment and during treatment.

Question 8

How frequently heart investigations are required?

Accepted Answer

Heart investigations should be performed at the starting of the treatment. It should be repeated every 3 months during treatment and every 6 months after the discontinuation of treatment until 24 months from the last administration of Canmab 440mg Injection. Those patients who already have heart-related problems will require investigations every 12 weeks.

CANMAB 440MG INJECTION

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