Question 1

Is it safe to use Brustan 400mg/325mg Tablet?

Accepted Answer

Brustan 400mg/325mg Tablet is safe for most patients. However, in some patients, it may cause some unwanted side effects like nausea, vomiting, stomach pain, heartburn and diarrhea. Inform your doctor if you experience any persistent problem due to this medication.

Question 2

Can I stop taking Brustan 400mg/325mg Tablet when my pain is relieved?

Accepted Answer

Brustan 400mg/325mg Tablet should be continued as advised by your doctor, if you are using the medicine for a condition associated with long-term pain. It can be discontinued if you are using it for short-term pain relief.

Question 3

Can the use of Brustan 400mg/325mg Tablet cause nausea and vomiting?

Accepted Answer

Yes, the use of Brustan 400mg/325mg Tablet may cause nausea and vomiting. Taking it with milk, food or antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine or a low frequency of urination. Do not take any other medicines without speaking to your doctor.

Question 4

Can the use of Brustan 400mg/325mg Tablet cause dizziness?

Accepted Answer

Yes, the use of Brustan 400mg/325mg Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, do not drive or use any machines. It is better to rest for sometime and resume once you feel better.

Question 5

Are there any specific contraindications associated with the use of Brustan 400mg/325mg Tablet?

Accepted Answer

The use of Brustan 400mg/325mg Tablet is considered to be harmful for patients with known allergy to any of the components of this medicine. It should be avoided in patients with known allergy to other painkillers (NSAIDs). The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active or recurrent stomach ulcer/bleeding. It should also be avoided in patients with history of heart failure, high blood pressure, and liver or kidney disease.

Question 6

Is Brustan 400mg/325mg Tablet helpful in relieving stomach pain?

Accepted Answer

No, Brustan 400mg/325mg Tablet should not be taken for stomach pain without consulting a physician. This drug can increase stomach acid secretion which may aggravate an unknown underlying condition.

Question 7

Can the use of Brustan 400mg/325mg Tablet cause damage to kidneys?

Accepted Answer

Yes, the long-term use of Brustan 400mg/325mg Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protect the kidneys from damage. Use of painkillers lowers the levels of prostaglandins in the body, leading to kidney damage because of long-term use. Therefore, the use of painkillers is not recommended in patients with underlying kidney disease.

Question 8

Is it safe to take a higher than the recommended dose of Brustan 400mg/325mg Tablet ?

Accepted Answer

No, taking a higher than the recommended dose of Brustan 400mg/325mg Tablet can increase the risks of side effects like nausea, vomiting, heartburn, indigestion and diarrhea. In fact, using this medicine for a long-term can also damage your kidneys on long-term use. If you are experiencing increased severity of pain or if the pain is not relieved by the recommended doses of this medicine, please consult your doctor for re-evaluation.

Question 9

Is this medicine addictive?

Accepted Answer

No, this medicine is not addictive but it is advised not to give this medicine if anyone else has the same condition like you.

Question 10

What are COX inhibitors? Is Brustan Tablet a COX inhibitor?

Accepted Answer

COX or cyclooxygenase inhibitors block the enzyme cyclooxygenase which secretes substances in injury or illness that promote pain and inflammation. There are 2 forms of this enzyme called COX-1 and COX-2. While some medicines selectively inhibit COX-1 (Aspirin, Indomethacin) or COX-2 (Etoricoxib, Valdecoxib), Brustan Tablet inhibits both the enzymes. Brustan Tablet may increase the intensity of adverse effects when used in combination with other COX inhibitors and hence caution is advised.

Question 11

Is there anything else I need to know before taking Brustan Tablet?

Accepted Answer

There should be a minimum 6-hour gap between 2 Tablets of Brustan Tablet and you should not take more than 3 Tablets in 24 hours. It is not recommended to use this medicine for more than 4 days on self-prescription. If you have use for a longer period, consult your doctor. This medicine should not be used in children below 12 years of age and who weigh less than 40 kg. (if >12 yrs old).

Question 12

Why do pain killers cause gastrointestinal bleeding?

Accepted Answer

Pain killers (NSAIDs) irritate or damage the lining of the stomach which results in stomach bleeding. This lead to formation of ulcers or in perforation. However, this does not occur in normal doses and is especially a concern if you are taking pain killers for a prolonged period or use them more than regularly. The risk of gastrointestinal bleeding, ulcers and perforation is higher with higher doses.

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