Question 1

What is Amaryl M 1mg Tablet PR?

Accepted Answer

Amaryl M 1mg Tablet PR is a combination of two medicines: glimepiride and metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with a proper diet and regular exercise. Glimepiride lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.

Question 2

Can the use of Amaryl M 1mg Tablet PR lead to lactic acidosis?

Accepted Answer

Yes, the use of Amaryl M 1mg Tablet PR can lead to lactic acidosis. It is a medical emergency that is caused by increased levels of lactic acid in the blood. It is also known as MALA (metformin-associated lactic acidosis). It is a rare side effect associated with the use of metformin, and therefore, it is considered to be harmful for patients with underlying kidney disease, older patients, or those who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, a feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain, or a slow heart rate. If you have these symptoms, stop taking Amaryl M 1mg Tablet PR and consult your doctor immediately.

Question 3

What are the possible side effects of Amaryl M 1mg Tablet PR?

Accepted Answer

The use of Amaryl M 1mg Tablet PR is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, and headache. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to vitamin B12 deficiency.

Question 4

Can the use of Amaryl M 1mg Tablet PR lead to Vitamin B12 deficiency?

Accepted Answer

Yes, the use of Amaryl M 1mg Tablet PR can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can experience tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.

Question 5

Can the use of Amaryl M 1mg Tablet PR cause hypoglycemia?

Accepted Answer

Yes, the use of Amaryl M 1mg Tablet PR can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise, or take other antidiabetic medicines along with it. So, regular monitoring of the blood sugar level is important. Always keep a quick source of sugar, like glucose tablets, honey, or fruit juice, with you.

Question 6

Is it safe to take alcohol while I am also taking Amaryl M 1mg Tablet PR?

Accepted Answer

No, it is not safe to take Amaryl M 1mg Tablet PR along with alcohol, as it may lower your blood sugar levels and lead to hypoglycemia. It can also increase the chances of lactic acidosis.

Question 7

What are the recommended storage conditions for Amaryl M 1mg Tablet PR?

Accepted Answer

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, or other people.

AMARYL M 1MG TABLET PR

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